- Characteristics of the drug Palin
- Cystitis use
- special instructions
- Side effects
Palin: instructions for use for cystitis and how to take an antibiotic for prostatitis
Instructions for use of the drug Palin with cystitis, dosage and side effects. To whom it helps, the course of treatment and whether there are analogues. Contraindications to taking medication.
How to take the drug Palin with cystitis: dosage and side effects
The treatment of acute or chronic cystitis differs depending on the cause of the disease. If these are bacteria, antibacterial agents are prescribed to patients, for example, Palin. The feasibility of their use is determined on the basis of the results of laboratory tests that help identify disease strains and select an effective therapy. Instructions for use of Palin in cystitis is intended to familiarize yourself with general information about the drug. The treatment scheme is selected by a doctor who takes into account the peculiarities of the course of the disease and the patient’s state of health.
The content of the article
- Characteristics of the drug Palin
- Composition and class of substance
- Mechanism of action
- Release form
- Pharmacodynamics and pharmacokinetics
Characteristics of the drug Palin
Palin is an antibacterial drug that is used to eliminate infectious diseases of the urinary tract. Acts on the majority of gram-positive and gram-negative representatives of the bacterial omnadrenu flora.
- E. coli;
- streptococci, including golden;
- Neisseria and others.
Anaerobic microorganisms and protozoa are insensitive to it. In case of mixed infections, the therapy is supplemented with other drugs.
Composition and class of substance
Palin is an antibiotic of synthetic origin, which has a wide spectrum of action and is a member of the quinolone (fluoroquinolone) series. The main component is pipemidovaya acid.
Other substances used in the composition:
- silica (colloidal);
- corn starch;
- stearic acid.
The capsule shell includes gelatin, colorants and titanium dioxide.
Mechanism of action
Pipemidovy acid has a pronounced antibacterial effect. The use of high doses leads to the death of pathogens. At low concentrations, their reproduction slows down.
Depending on the situation, the drug can be used as a single agent or in combination with additional medications – antibiotics from other groups, antiprotozoal drugs and others.
The drug comes in the form of gelatin capsules (200 mg of active ingredient). Manufacturer manufacturer Sandoz (Slovenia). In 1 carton box 2 blisters of 10 capsules. Other dosage forms are not provided. Analogues based on pipemidovoy acid are found in the form of tablets.
An antibiotic expiration date of 5 years from the date of production. The maximum permissible storage temperature is 25 ° C.
The condition of the release of the pharmacy chains – a prescription.
Pharmacodynamics and pharmacokinetics
The effectiveness of the antibiotic in diseases of the genitourinary system due to the peculiarity of the distribution of the active substance in the tissues. A high content of pipemidic acid is noted in the kidneys and the prostate gland, so Palin gives an equally good result for prostatitis, cystitis, pyelonephritis and other pathologies.
The antibiotic is rapidly absorbed in the digestive tract. The maximum plasma concentration is determined 70–80 minutes after oral administration.
The drug passes through the placenta and can have a systemic effect on the fetus. A small amount of the chemical is excreted along with breast milk.
The antibacterial effect of the drug is achieved due to the bactericidal or bacteriostatic effect on sensitive microorganisms.
Most of the active component excreted in the urine unchanged. The intensity depends on creatinine clearance (the rate at which blood passes through the kidneys). A small amount stanabol tablets goes along with the bile.
The lack of a therapeutic effect may be due to:
- impaired absorption in the gastrointestinal tract (gastrointestinal tract);
- use of the drug without prior diagnosis;
- development of resistance to pipemidovoy acid.
Before starting the course of treatment, it is necessary to pass urine sap with an antibiogram. This will help identify the causative agents of urological disease and select effective drugs.
The drug is used to treat acute or chronic pathologies of the urinary tract, triggered by sensitive flora.
It is prescribed for cystitis, urethritis, pyelonephritis, prostatitis, or to prevent infection after surgical interventions.
How to take Palin with cystitis depends on the diagnosis and neglect of the disease. The average course duration is 5–10 days. In mild cases, 3 days is enough. Chronic recurrent infections treat longer, usually about a month.
To eliminate cystitis, 400 mg (2 pcs.) Of pipemidic acid is used twice a day, in the morning and evening. Capsules are taken after a meal, drinking plenty of liquids.
During treatment, it is recommended to take into account some features of the drug. This will help to increase its effectiveness and reduce the likelihood of adverse reactions.
The official instructions for use contain the following instructions:
- patients with severe impaired renal function require dosage adjustment;
- with normal creatinine clearance, it is recommended to drink plenty of fluids and monitor the level of excreted urine;
- The treatment of the elderly (over 70 years old) is carried out with caution, since in this group of patients the side effects are more pronounced;
- pimemidic acid has a photosensitizing property, so during treatment it is necessary to avoid direct sunlight on the skin and to avoid sources of artificial ultraviolet radiation (for example, tanning beds);
- uncontrolled use of antibiotic leads to the development of superinfection and reduce the effectiveness of therapy;
- when driving and other activities that require increased attention, care must be taken.
Often the antibiotic is well tolerated.
Some patients may have the following complaints:
- nervous excitement;
- lack of coordination of movements;
- depressive states;
- sleep problems;
- trembling limbs;
- severe diarrhea.
In patients with severely impaired renal function, the number of platelets in the blood sometimes drops, which is clinically manifested by increased bleeding.
Taking the drug with a deficiency of glucose-6-phosphate dehydrogenase is fraught with the development of severe hemolytic anemia.
When individual intolerance of the components appear skin symptoms – rash, itching.
The antibiotic is intended for the treatment of adult women and men. In pediatric practice is not used.
- severe renal impairment;
- pregnancy and lactation;
- deficiency of glucose-6-phosphate dehydrogenase;
- epilepsy and other serious pathologies of the nervous system and brain;
- individual intolerance to quinolones or other components of the drug.
Intentionally or accidentally exceeding the recommended dosages leads to increased side effects.
The following complaints come to the fore:
- nausea and vomiting.
If the victim is conscious, he needs to wash the stomach and give activated charcoal. Otherwise, hospitalization and hemodialysis are indicated. This cleaning procedure removes 90% of pipemidic acid from the body and quickly improves well-being.
In case of marked disorders of the central nervous system, symptomatic therapy is carried out in accordance with the recommendations of the doctor.
Palin analogs are divided into two groups – identical in the active substance or similar in pharmacological properties.
The first group includes:
The main component of these drugs is pipemidic acid, so their characteristics are very similar. Differs release form, additional composition and cost.
The second group includes fluoroquinolone antibiotics:
- Ciprofloxacin and others.
They have a similar effect on sensitive microorganisms, but differ in the form of release and other characteristics, therefore, prior to their use, consultation of a physician and careful study of the instructions for use are required.
Self-treatment of acute cystitis led to the transition of the disease to the chronic form and regular relapses. Earlier, on the recommendation of a doctor, I used meralucil suppositories and Monural. Such treatment eliminated only the symptoms that were t3 liothyronine bodybuilding constantly returning. Then the doctor prescribed antibiotic Palin, and, to my great surprise, the result appeared very quickly. The pain receded the next day, there were no side effects, and cystitis has not bothered for more than a year.
Chronic cystitis sick for a long time. Every autumn there is a stable relapse, terrible pains and long treatment. Tried a lot of antibiotics. The result was, but not immediately. One day a nurse in the hospital advised Palin to try. Now this drug is always stored in the first-aid kit, because it helps quickly and is well tolerated.Nina, 55 years old (Taganrog)
Palin saw on the advice of her friends, but, apart from side effects, did not notice the results. My head hurt badly, my skin began to itch, so I stopped the experiments and went to the doctor. The test results showed that the cause of my illness was Trichomonas, which had penetrated the bladder from the vagina. As a result, Metronidazole was cured, and Palin in my case was superfluous, because it does not act on this group of microorganisms.Valeria, 28 years old (Kolomna)
Most patients and doctors consider Palin to be an effective remedy for chronic or acute cystitis. The main advantages are a quick result, a decrease in the number of relapses, and good tolerability. The disadvantage is relatively high price. The lack of a therapeutic effect is often associated with the incorrect prescription of a drug, for example, when people drink it on the advice of friends or pharmacists in a pharmacy, although even in this case the medication helps a lot.
What is cystitis, why it occurs and how to get rid of it, you can learn from the video.